HongKong-JSS # An effortless Synthetic Biological Formaldehyde Monitoring Device # Our project is inspired by the prevalent issue of indoor air formaldehyde pollution in newly renovated houses in Hong Kong. 私たちのプロジェクトは、香港の新しく改装された家における室内空気中のホルムアルデヒド汚染という広く存在する問題にインスパイアされています。 reference: iGEM HongKong-JSS Team Information iGEM HongKong-JSS Wiki
HongKong-PuiChing # Dimstar: a Silent Treatment on Chronic Liver Disease # Chronic liver disease is on account of approximately 2 million fatalities annually worldwide., being the 11th leading cause of death. Our team aims to prevent this disease by producing a gene with Gata4 protein, then introducing the gene to red blood cells as carriers via liposomes, transporting it to the liver cell for curing and diagnosing liver fibrosis. ...
HS-China # A one-pot isothermal Cas12-based assay for the sensitive detection of COPD # Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disorder characterized by progressive lung function decline and is a leading cause of mortality worldwide. Early and accurate diagnosis of COPD is crucial for effective management and intervention strategies. In this project, we aim to utilize the diagnostic potential of miRNA biomarkers, specifically miR223 and miR1274a, coupled with the reverse transcription polymerase chain reaction (RT-PCR) method. ...
HS-Shanghai # – Not provided yet – # – No abstract provided yet – – まだ要約が提供されていません – reference: iGEM HS-Shanghai Team Information iGEM HS-Shanghai Wiki
HSASNU # Development of a Detector Used For Early Screening of Atherosclerosis # The cardiovascular and cerebrovascular diseases (CCVD) caused by atherosclerosis (AS) rank first among various causes of death in the world, especially in an aging society, such as China. In our project, we endeavored to develop a detector used for the early screening of AS by detecting trimethylamine N-oxide (TMAO) and microRNAs (miR-17-5p and miR-146a-5p), all of which were reported high concentration in the urine of patients. ...
iBowu-China # BeePystErase: A Synthetic Biology Approach for Bio-Degradation of Pyrethroids # Our project in 2023 addresses the environmental concerns of pyrethroids, synthetic pesticides with detrimental effects on non-target, neutral creatures like bees. Despite the chemical’s market prevalence, pyrethroid’s neurotoxicity and ecosystem imbalances necessitate urgent remediation strategies. Our approach harnesses carboxylesterases to degrade pyrethroids into less harmful metabolites. Multiple enzymes from various species were identifies, cloned and expressed in E. ...
ISPanama # Detection of Fosarium Oxysporum through quorom sensing of Rhizobium leguminosarum using E.coli as a model # Panama is a significant banana producer in Latin America, yielding approximately 2.5 million tons annually, contributing about $200 million to Panama’s economy. Currently, there are no ultimate solutions to manage the spread of Fusarium oxysporum, an asexual-reproducing fungal pathogen that can remain in soil, tissue, and organic residues asymptomatically in an endophyte form. ...
Japan-United # saffrocure:Innovative Approaches to Depression Treatment # Worldwide, over 320 million people suffer from depression, leading to economic losses of over $18.4 billion in Japan alone. While treatments and medications exist, there’s insufficient focus on prevention and everyday mental health care. To address this issue, we’re leveraging saffron, a flower cultivated in Japan for centuries. Saffron contains three antidepressant compounds, which we aim to produce using synthetic biology in E. ...
Jiangsu-United # FlexiCarti: Bones and Joints, Healthy Growing # The prevalence of osteoarthritis (OA) is on the rise due to the aging population and the increasing rate of obesity. OA severely impacts the life quality of patients; unfortunately, no effective therapeutic strategy currently exists owing to its complicated pathology. Recent studies have found that the expression of osteoglycin (OGN) was significantly reduced in the articular cartilage of patients with OA. ...
KCIS-Xiugang-Taipei # Brew to First Aid: An environmental-friendly answer to leather # The leather industry is harmful to the environment: endangered animals are killed for products, cattle needed for leather produce greenhouse gases; chemicals used to process animal skin pollute the environment and create health problems for workers involved. This inspired us to tackle the leather industry with a more sustainable approach: SCOBY (symbiotic culture of bacteria and yeast). SCOBY contains lactic acid bacteria, acetic acid, bacteria, and yeast, and forms a bacterial cellulose membrane by tangling secreted cellulose fibrins. ...