October 21, 2023
CNAS-Romania # Engineered Cyanobacteria For A Greener Future # Cyanobacteria are one of the first life forms to appear on Earth. Microorganisms capable of producing oxygen through photosynthesis, they live both in salt and freshwater. However, when their environment is polluted, they can cause algae blooms that are harmful to the ecosystem. Alcanivorax borkumensis is a type of bacteria that has the ability to break down alkanes, essentially decomposing petroleum into non-toxic components.
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October 21, 2023
CollegiateRVA # – Not provided yet – # – No abstract provided yet –
– まだ抄録が提供されていません –
reference:
iGEM CollegiateRVA Team Information iGEM CollegiateRVA Wiki
October 21, 2023
DNHS-SanDiego-CA # PlastiFind # Every year around 20 million tons of plastic waste leaks into aquatic ecosystems. Polyethylene terephthalate (PET) is a commonly used thermoplastic resin. Global accumulation of plastic can be counteracted by improving PET degradation in the environment. However, scientists currently lack efficient methods to measure PET hydrolysis, making it difficult to research further in this field. The goal of this project is to develop a sensitive plasmid biosensor to detect terephthalic acid (TPA), a byproduct of PET hydrolysis.
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October 21, 2023
EastCoastBioCrew # RhizeUP: Engineering Rhizobium to Combat the Root of Nutrient Runoff # Modern agricultural practices rely heavily on phosphate fertilizers. However, due to the tendency of phosphate to bond with minerals in the soil, most phosphate molecules exist in a form unusable to plants. These mineral phosphates are a driving force behind the nutrient pollution and runoff in waterways that leads to algal blooms. RhizeUP aims to engineer Rhizobium tropici, a nutrient-fixing soil bacteria known for its high tolerance to environmental stresses and which is a successful microsymbiont of several legumes.
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October 21, 2023
Example-HS # – Not provided yet – # – No abstract provided yet –
– まだ抄録が提供されていません –
reference:
iGEM Example-HS Team Information iGEM Example-HS Wiki
October 21, 2023
FDR-HBPeru # Plast"e.co": Transforming Plastic into Biofuel # Can we mitigate plastic pollution and simultaneously benefit our community?
私たちはプラスチック汚染を軽減し、同時にコミュニティに利益をもたらすことができるでしょうか？
reference:
iGEM FDR-HBPeru Team Information iGEM FDR-HBPeru Wiki
October 21, 2023
FSHS-GD # Novel antimicrobial peptides based on combinatorial biosynthetic strategies # The emergence of pathogen drug resistance poses a grave threat to public health, with the WHO predicting up to 10 million annual deaths from resistant infections by 2050. Conventional natural product screening approachs suffer from high rediscovery and low novelty rates. To address this issue, we focused on antimicrobial peptides which are microbial metabolites with high specificity and low side effects.
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October 21, 2023
Fujian-United # Synthesis of new feed additives through genetic engineering to express phytase with AppA and An_phy33 # The increasing scale of global livestock farming has led to a shortage in the supply of conventional feed protein raw materials in the feed industry and even the phenomenon of competition with people for food, livestock farming and processing are also prone to environmental problems such as water and soil pollution.We construct recombinant plasmids pYES2-AppA and pYES2-An_phy33, transform them into E.
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October 21, 2023
GEC-CHINA # Directed evolution to elevate bio-production of NAD+ for anti-ageing # As the aging population continues to grow, the treatment of aging and age-related diseases has become an important societal issue. NAD+ is a critical molecule in cellular metabolism and life span, but its levels decline with age. NAMPT is the key enzyme for NAD+ synthesis, however, the catalytic activity of human NAMPT is extremely low. Therefore, our project aims to harness the power of directed evolution to select the NAMPT mutant form with superior activity and accelerate the bio-production of NAD+ and its application in anti-aging therapy.
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October 21, 2023
GEC-Guangzhou # Targeted therapy for colorectal cancer # We used Nissle 1917 as the chassis microbe because it is safe, reliable and easy to edit for the human body. We designed two modules of targeting and therapy. For the targeted part, we fusion expression of INP and HIPA genes, INP can anchor HIPA to the cell wall of engineered bacteria, and HIPA protein can recognize and bind to the receptor protein on the surface of cancer cells.
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