October 21, 2023
YangzhouNOFLS # Paclisa: Development of PTX-ADC Elisa Kit # Our product is a monoclonal antibody for the detection of PTX in combination with an ELISA for the quantitative detection of small molecule PTX levels, with the goal of effectively supporting clinical studies for the development of ADC anticancer drugs. Moreover, we hope this product can offer more treatment possibilities for hard-to-treat cancers.
私たちの製品は、ADC抗がん薬の開発のための臨床研究を効果的に支援することを目指し、ELISAと組み合わせてPTXの検出のためのモノクローナル抗体、および微量PTXレベルの定量的な検出を提供します。さらに、この製品が難治性のがんの治療の可能性を更に広げることを願っています。
reference:
iGEM YangzhouNOFLS Team Information iGEM YangzhouNOFLS Wiki
October 21, 2023
YiYe-China # miRNA Sensor based on LncRNA MALAT1 for diagnosis of cervical cancer # Cervical cancer is the fourth most common cancer among women globally. Peppers plasmid is a newly developed tool that can be used for real-time, high-throughput quantification and even visualize the location of RNA in live cells. Noncoding RNAs (ncRNAs), including miRNA and lncRNA, modulate a wide array of growth and differentiation processes and become potential diagnostic biomarkers in cervical cancer.
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October 21, 2023
Zhejiang-United # Crisprologists: Optimized High-Efficiency Genome Editing Tool based on CRISPR-Cas9 System # When using CRISPR-Cas for gene editing, it is common to encounter cells that do not undergo the expected edits, thereby reducing the efficiency of CRISPR-Cas gene editing. To address this issue, we have employed a strategy of increasing the copy number of Cas9 to construct an efficient genome editing tool based on the CRISPR-Cas9 system for Nissle 1917.
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October 21, 2023
ZJFH-Nanjing # Cell Factory Of Sugar Substitute # Many people prefer to choosing sugar substitute while losing weight. However, the production of natural sugar substitutes (e.g., plant extraction method and chemical synthesis) has some limitations. Therefore, We aim to produce xylitol by transformation using Escherichia coli BL21, and realise the de novo synthesis of erythritol by Yarrowia lipolytica.
多くの人々は、体重を落とす際に砂糖の代替品を選ぶことを好みます。しかし、天然の砂糖代替品の生産（例えば、植物抽出法や化学合成）にはいくつかの制限があります。そのため、私たちは大腸菌BL21を用いた変換によりキシリトールを生産し、ヤロウイア・リポリティカによるエリトリトールのde novo合成を実現することを目指しています。
reference:
iGEM ZJFH-Nanjing Team Information iGEM ZJFH-Nanjing Wiki