October 21, 2023
SZ-SHD # Intelli-P # Phosphorus is vital for crop growth, yet its limited availability as insoluble phosphate salts in rocks necessitates resource-intensive processing into fertilizers, depleting finite reserves. Our team offers a comprehensive solution for a more sustainable future: a dual-pronged approach involving a phytosensor to detect crop phosphate requirements and a smart phosphate biofertilizer. The phytosensor, equipped with a low-phosphate-responsive promoter and a bright GFP reporter, facilitates cost-effective monitoring of phosphate levels in plants.
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October 21, 2023
Taipei-KCISLK-V1 # Worm Out Clots # We applied synthetic biology to address cardiovascular diseases in Taiwan – a pressing issue accounting for 22.5% of deaths among the elderly aged 65 or above. Through research, we found that lumbrokinase, an enzyme extracted from Lumbricus bistamus, holds promise in dissolving fibrin in thrombi, which are responsible for blood clotting and strokes. However, there were two issues: the high cost and moral implications of current lumbrokinase markets, as well as medication non-compliance and high-fat dietary habits among elderly patients with cardiovascular diseases.
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October 21, 2023
Thailand-RIS # Powering Up Plant Defense # A growing issue that farmers are facing is the degradation of their crop harvest as a result of extreme environmental conditions that cause stress to their plants—posing a threat to their livelihoods and causing adverse economic consequences. Team Thailand-RIS aims to alleviate this issue by modifying the Glutamate-cysteine ligase (GCL) gene which plays an important role in stress response via regulating the production of Glutathione (GSH).
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October 21, 2023
The-Kings-School-AU # Solutions for our Soil — Engineering Nitrogen Fixing Bacteria with Oxygen Sensing Capabilities # The overuse of synthetic nitrogen-based fertilisers has caused significant damage to ecosystems across the globe. Our project aims to use synthetic biology to engineer E. coli to produce ammonia naturally, in order to decrease the fossil fuels and nitrogen pollution impact of the fertiliser industry. SOILutions aims to develop an oxygen-sensing feature that allows the bacteria to activate only under low oxygen conditions, increasing the longevity and usability of these engineered microorganisms.
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October 21, 2023
THINKER-CHINA # A strain engineered that provides enough myrosinase to produce sulforaphane and prevents colorectal cancer # Colorectal cancer is a common malignant tumor in the gastrointestinal tract and a high incidence tumor worldwide. However, after investigation, we realised that cruciferous plants is rich in high concentrations of glucosinolate, it can be hydrolyzed by myrosinase to sulforaphane, sulforaphane has strong anticancer activity and antioxidant capacity which is good at preventing colorectal cancer.
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October 21, 2023
Thinker-Guangdong # Conservation of Ancient Buildings Using MICP Technology-Microbial Cement # Ancient buildings are “living cultural relics, living history” that have carried the history for thousands of years, so restoration of ancient roofs is of great significance to the transmission of history. However, because of the loss of ancient restoration methods, we wanted to use microbial-induced carbonate precipitation to fill in the cracks in the artefacts and strengthen them while preventing further damage.
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October 21, 2023
Thinker-SC # Technology Green Finger: Genetically engineered E. coli helps innovative acetic acid seeds prevent soil erosion # Soil erosion is a major environmental problem. We use genetic engineering technology to innovatively launch acetic acid seeds - indole acetic acid, in order to alleviate this problem. We introduced the key enzyme responsible for the production of IAA into engineered E. coli so that it can produce IAA. In order to strengthen soil remediation, E.
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October 21, 2023
Thinker-Shanghai # Modifiyng microbes to degrade cholesterol to prevent cardiovascular diseases such as arteriosclerosis # In recent years, statistical data has shown a significant increase in the prevalence of high cholesterol related diseases due to changes in dietary habits. There is a higher frequency of processed foods being consumed. These foods are rich in high-cholesterol ingredients which inevitably leads to higher risks of various cardiovascular diseases and other health issues.
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October 21, 2023
Thinker-Shenzhen # Revolutionizing Agriculture: Genetic Engineering for Sustainable Alginate Oligosaccharide Biofertilizers from Algae # Our project, inspired by previous iGEM teams, addresses eutrophication’s environmental impact on rivers and oceans. Eutrophication, driven by excessive algae growth, harms ecosystems by depleting oxygen levels through photosynthesis. Typical treatments discard excess algae, creating waste.
私たちのプロジェクトは、以前のiGEMチームに触発され、河川や海洋への富栄養化の環境への影響に対処しています。富栄養化は、過剰な藻類の成長により進行し、光合成を通じて酸素レベルを枯渇させることで生態系を損ないます。典型的な治療法では、余分な藻類を破棄し、廃棄物を作り出します。
reference:
iGEM Thinker-Shenzhen Team Information iGEM Thinker-Shenzhen Wiki
October 21, 2023
THIS-CHINA # Engineering Herbicide Resistance: Mutations in The Acetolactate Synthase Binding Domain to Confer Herbicide Resistance # Herbicide resistance among weeds in farmland is a growing concern in sustainable agriculture. In this project, we will focus on Penoxsulam, which is a herbicide that targets the acetolactate synthase (ALS) enzyme in plants, blocking the biosynthesis pathway of Valine Leucine and Isoleucine, leading to growth inhibition. This project aims to engineer a Penoxsulam-resistant ALS enzyme in Rice (Oryza sativa subsp.
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