October 21, 2023
Chalmers-Gothenburg # SoDoVi - Essential Vitamins from Sourdough # This years project focused on the metabolic pathways of yeast and lactobacillus to try and produce a sourdough, containing the respective microbe, that produced essential vitamins. We designed this to be done by introducing foreign genome from other species of bacteria. Our hope for the project to help combat the issue of malnutrition concerning vitamin A, and offer an alternative source of B12 besides animal based products.
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October 21, 2023
Guelph # Project BloomBiota: Combatting vitamin B12 Deficiency with probiotic-expressed gastric intrinsic factor # Project BloomBiota aimed to create a probiotic containing enriched B12 and human gastric intrinsic factor (hGIF) to combat vitamin B12 deficiency, which disproportionately affects women, vegetarians, and the elderly. Through one pill containing the probiotic strain of Escherichia coli Nissle 1917, an individual receives a B12 supplement and increased absorption. BloomBiota is novel because it aims to express hGIF in the bacterial periplasm instead of the cytoplasm, which increases the chances for proper folding, resulting in a functional protein.
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October 21, 2023
HKUST # Cereulight – Be “Cereus”, Be Cereu-Free, with Cereulight ! # Cereulide is a food toxin produced by Bacillus cereus that is mainly found in pre-cooked starchy food. To detect cereulide in food samples, our team aims to create a low-cost, user-friendly colorimetric biosensor that can detect high levels of cereulide on-site, to prevent possible symptoms from cereulide poisoning including but not limited to vomiting, nausea, and potential liver damage.
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October 21, 2023
HUST-UEVE-UPSaclay # – Not provided yet – # – No abstract provided yet –
– まだ要約が提供されていません –
reference:
iGEM HUST-UEVE-UPSaclay Team Information iGEM HUST-UEVE-UPSaclay Wiki
October 21, 2023
ICT-Mumbai # Reducing phytate content in legumes and millets using engineered baker’s yeast # Phytate is an antinutritional factor found in legumes and millets. While these are staple food items in many regions of the world, there is a need to decrease phytate content to enhance their nutritional value. Treatment of the flour with phytase enzyme is an option, but it increases the cost and a unit operation. We have therefore engineered baker’s yeast, Saccharomyces cerevisiae, to express phytases.
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October 21, 2023
LZU-CHINA # Intelligent cholesterol management system # High-fat diets in the modern world have led to a significant impact on cardiovascular health. Conditions such as hypercholesterolemia, atherosclerosis, osteoporosis, and various cardiovascular diseases resulting from excessive cholesterol intake are of great concern. Current clinical treatments primarily rely on medication to control cholesterol levels, but they come with associated side effects, creating new health risks. To address these issues, LZU-CHINA has developed a probiotic-based cholesterol-regulating system, using an oleic acid inducer as the promoter module.
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October 21, 2023
NAU-CHINA # BISTRO：Biological Sensing, Tracking, and Reduction of Ochratoxin A # This project focuses on detecting and degrading ochratoxin A (OTA) in red wine, a popular global beverage. OTA is a toxic mycotoxin widely present in wine, posing health risks. By using specific binding and amplification techniques, the detection module enables convenient OTA detection. The degradation module utilizes probiotics to create a functional polymer network with the OTA-degrading enzyme M-CPA, effectively converting OTA into non-toxic compounds.
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October 21, 2023
NPU-CHINA # EnzyArt scout：A smart enzymology based nitrite detector and degrader # This project aims to develop an enzyme-based electrochemical sensor for highly convenient detection and precise dynamic regulation of nitrite levels.
このプロジェクトは、ニトライトレベルの非常に便利な検出および精密な動的調節のための酵素ベースの電気化学センサーを開発することを目指しています。
reference:
iGEM NPU-CHINA Team Information iGEM NPU-CHINA Wiki
October 21, 2023
Tec-Chihuahua # AureoBos: Recombinant Enzibiotics as The Future of Non-Antibiotic Bovine Mastitis Treatment # Bovine mastitis, an inflammatory udder infection caused by gram-positive and gram-negative bacteria, annually affects 5.4 million dairy cattle, impacting milk production, causing wastage and rising prices. Conventional antibiotic treatment exacerbates the issue by fostering bacterial resistance. We pioneer non-antibiotic bovine mastitis treatment, addressing global needs while minimizing risks. Aureobos, is an intramammary infusion of endolysins, antimicrobial enzymes known for their specificity, effectiveness against antibiotic-resistant strains, and limited development of resistance.
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October 21, 2023
UPNAvarra-Spain # ResVinoLife: unlocking the power of resveratrol # In Navarre, the wine industry holds vital importance. It is estimated to produce over 83 million liters annually, encompassing six designations of origin and spanning 13,300 hectares of dedicated vineyards. During the wine production process, 25% of the grapes end up as waste, with grape skins accounting for 50% of this waste. However, grape skins possess significant value. They contain a highly nutritious compound called resveratrol, a potent antioxidant known for its protective properties against certain cancers and its anti-aging effects.
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