RPTU-Kaiserslautern # CYPurify - The Solution to Pollution # Water is the foundation for all life. However, the integrity of our waters is far from a reality. While society is aware of the pollution caused by oil and plastic, there is far less awareness of the ever-increasing amount of chemicals being introduced and leaking into groundwater, rivers, and lakes. There, they threaten the ecosystem on both a small and large scale. ...
SDU-Denmark # In Vitro Optimization of Dehalogenases for PFAS Degradation # PFAS (per- and polyfluoroalkyl substances) pollution has garnered significant media attention in Denmark, due to its detrimental impact on groundwater and human health. A primary challenge lies in degrading PFAS, given the highly stable carbon-fluorine bonds present in their structure. PFAS（パーおよびポリフルオロアルキル物質）の汚染は、地下水と人間の健康に対する有害な影響のため、デンマークで大きなメディアの注目を集めています。主な課題は、その構造に存在する非常に安定した炭素-フッ素結合のため、PFASを分解することにあります。 reference: iGEM SDU-Denmark Team Information iGEM SDU-Denmark Wiki
SJTU-BioX-Shanghai # The MONCKIE King # For iGEM 2023, SJTU-BioX-Shanghai targeted residual heavy metal pollution in waters with the Metal-iON-Cleaning and KnItting E. coli (MONCKIE). Inspired by the Monkey King and his hair-made clones, we utilized the engineered outer membrane vesicles (OMVs) instead of E. coli to remove heavy metal ions from water. We are displaying heavy metal binding proteins, OMV recovery modules and cross-linking modules on the surface of the OMVs. ...
Sorbonne-U-Paris # PseudoDetox # Pseudodeteox project aims to improve the bioremediation of polycyclic aromatic hydrocarbons (PAHs), ones of the most pollutings in soils. Pseudodeteoxプロジェクトの目的は、多環芳香族炭化水素（PAHs）という、土壌で最も汚染物質と確認されているものの生物修復を向上させることです。 reference: iGEM Sorbonne-U-Paris Team Information iGEM Sorbonne-U-Paris Wiki
Thessaly # oPHAelia: From Waste to Worth # Olive Oil Mill Wastewater (OMW) is a toxic by-product of olive oil production. Greece is the third-largest olive oil producer globally, and in our region, Thessaly, OMW poses a significant problem due to the substantial quantities generated every year. The absence of effective OMW management methods has posed challenges for olive oil producers, often resulting in improper disposal that threatens the environment. ...
TJUSLS-China # P-eat: A targeted mutation of PEase to improve thermostability # Polyethylene plastic (PE) can be seen everywhere in our lives. High production and low recovery rate make PE plastic pollution a worldwide environmental problem. Current treatment of PE requires the oxidation of C-C bond using physical or chemical methods. PEase, discovered recently, is the only enzyme that can oxidize PE at room temperature. However, PE plastics will change their internal molecular arrangement and are more likely to be oxidized at high temperatures. ...
TU-Dresden # DRIP: Diatom-based Remediation using Immobilized Proteins in Thalassiosira pseudonana # Water quality is threatened by micropollutants and microplastics. Since conventional wastewater treatment plants are not able to effectively remove these micropollutants, they end up in nature where they can exert negative effects on various organisms. 水質は微量汚染物質とマイクロプラスチックによって脅かされています。従来の下水処理施設ではこれらの微量汚染物質を効果的に除去することができず、結果的に自然界に排出されて様々な生物に対して悪影響を及ぼすことがあります。 reference: iGEM TU-Dresden Team Information iGEM TU-Dresden Wiki
UConn # Degradation of 17α-ethynylestradiol by Genetically Engineering the CotA Laccase Gene of Bacillus licheniformis # The synthetic estrogen hormone 17α-ethynylestradiol (EE2) is a common degradation-resistant pharmaceutical that causes fertility disruption in aquatic organisms. EE2 enters waterways through sewage effluent and run-off from livestock activities. Wastewater treatment facilities provide an important role in reducing EE2, however, the degradation process is often incomplete. We aimed to design a bacterium that can more completely degrade EE2 in the wastewater treatment system. ...
UCSC # Toxic Algal Bloom Interference # Harmful algal blooms (HABs) are increasing in prevalence due to warming temperatures; this threatens the utility and biodiversity of freshwater ecosystems globally. The cyanobacteria Microcystis aeruginosa secretes microcystin, a hepatotoxin that is the principal contributor to this threat. Remediation of HABs can be accomplished with synthetic biology, but efficiently transforming M. aeruginosa is difficult due to targeting of foreign DNA by restriction-modification systems. ...
UESTC-China # E.coli air guard # With every breath, there are tons of substances that go into our body, air quality and our health are closely linked. However, air is more dangerous than we think. 私たちが一息つくたびに、無数の物質が私たちの体に入り込みます。空気の質と私たちの健康は密接に関連しています。しかし、私たちが考えている以上に、空気は危険なものなのです。 reference: iGEM UESTC-China Team Information iGEM UESTC-China Wiki