October 21, 2023
Jiangnan-China # Efficient stereoselective hydroxylation of deoxycholic acid by the robust whole-cell Cytochrome P450 CYP107D1 biocatalyst # Deoxycholic acid (DCA) has been authorized by Federal Drug Agency for the cosmetic reduction of redundant submental fat. The hydroxylated product (6β-OH DCA) was developed to improve the solubility and pharmaceutic properties of DCA for further applications. Herein, a combinatorial strategy was applied to construct a powerful Cytochrome P450 biocatalyst (CYP107D1, Olep) to convert DCA to 6β-OH DCA.
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October 21, 2023
KULeuven # YarroWCO: the transformation of waste cooking oil into medicine # One liter of waste cooking oil (WCO) can contaminate a million liters of potable water. Humanity currently produces billions of tons of WCO yearly, with limited routes for its safe disposal, making it a threat to our environment. We propose to harness the yeast Yarrowia lipolytica to go beyond decontamination: our goal is to upcycle WCO into campesterol, an important steroid precursor for the pharmaceutical industry.
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October 21, 2023
Leiden # PHAse Out: Transforming Agriculture with Biodegradable Plastics using Green Methanol # Every day, we ingest microplastics through the food we eat, posing a major risk to our health. A major part of these plastics comes from agriculture, where plastic-containing fertilizers and mulch films break down and cause pollution. We, PHAse out, want to change this! Our goal is to replace conventional plastics in agriculture with biodegradable alternatives. Most importantly, our approach does not utilize valuable agricultural feedstocks, unlike most other biotechnological approaches.
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October 21, 2023
MSP-Maastricht # Sublimestone: A Dual Microbial System for the Restoration of Limestone Buildings # What do the Great Pyramid of Giza, the Parthenon and the Empire State Building have in common? They are all made from the same building material: limestone. These and many other limestone architectural gems are deteriorating at an alarming rate due to environmental factors enhanced by climate change, such as acid rain, prolonged rain seasons and air pollutants.
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October 21, 2023
Nanjing-China # Rainboweaver：Creating vibrant cellulose fibers, dedicated to fostering sustainable growth within the fashion industry # In today’s fast fashion industry, an astonishing 100 billion new garments are manufactured worldwide annually. Unfortunately, the process of dyeing clothing with lipophilic dyes like indigoidine stands out as the most detrimental environmental factor within production cycle. Rainboweaver endeavors to present a truly innovative solution. Building upon previous iGEM research, firstly, we optimized K.
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October 21, 2023
NEFU-China # Opticafé # Myopia has become a prominent factor leading to permanent blindness worldwide. Traditional methods have drawbacks like low efficacy, side effects. A novel and convenient method for treating myopia is urgently needed in modern society. 7-mythylxanthine(7-MX) is a promising compound to alleviate myopia by delaying the elongation of the eye axis. However, further development and utilization of 7-MX are inhibited by its lofty price. Our project made it possible to produce 7-MX with coffee residues as the materials.
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October 21, 2023
NEU-CHINA # Functional biofilms applied in metal corrosion protection # In metal corrosion protection, biofilm can play a role in metal corrosion protection by removing corrosive cathode medium (such as oxygen), inhibiting the growth of corrosive microorganisms, and forming a protective layer on the metal surface. However, one of the shortcomings of biofilm for metal corrosion protection is its weak metal adhesion ability. NEU-CHINA team aimed to design a living functional biofilm that can be applied to marine metal corrosion protection.
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October 21, 2023
NJTech-China-B # 1,5-PDO factory：Engineering Escherichia coli for the de novo production of 1,5-pentanediol # 1,5-Pentanediol (1,5-PDO) is one typical C5 diol commonly used as a building block for the production of polyurethane coating and have a broad market. Currently, commercial manufacture of 1,5-PDO entirely relies on petroleum feedstock, which is constrained by the limited accessible C5 petroleum feedstocks. In our work, we developed a cell factoryĀto produce 1,5-PDO from glucose in Escherichia coli through the synthetic biology tools.
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October 21, 2023
NYCU-Formosa # – Not provided yet – # – No abstract provided yet –
– まだ抄録が提供されていません –
reference:
iGEM NYCU-Formosa Team Information iGEM NYCU-Formosa Wiki
October 21, 2023
NYU-Abu-Dhabi # HypeColl: Biomanufacturing of Biomimietic Bacterial Collagen-Like Protein # Collagen is ubiquitous in the human body making it widely used in applications ranging from tissue engineering and regenerative medicine to cosmetics and supplements. Collagen is often sourced from animal sources leading to ethical, social, and even religious concerns. Through HypeColl, we aim to produce a bacterial collagen-like protein (CLP), Scl2.28-1. CLPs are thermally stable at body temperature but do not form collagen fibers.
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