October 21, 2023
AshesiGhana # Revolutionizing Lithium Prospecting and recycling in Ghana: The BioLith Solution # The process of detecting and extracting lithium currently involves extensive, environmentally damaging mining practices, consuming significant time, resources, and leading to landscape destruction and water pollution. Furthermore, the disposal of lithium-ion batteries poses a waste management challenge, with Ghana grappling with e-waste dumping.
リチウムの検出と抽出のプロセスは、現在、環境に負担をかける大規模な鉱業活動を伴い、膨大な時間と資源を消費し、風景の破壊や水質汚染につながっています。さらに、リチウムイオンバッテリーの廃棄は廃棄物管理の課題を引き起こし、ガーナは電子廃棄物のダンピングに対処しています。
reference:
iGEM AshesiGhana Team Information iGEM AshesiGhana Wiki
October 21, 2023
BIT-China # Lights control iT: Light-induced Controlled Synthesis of intermixed Terpenoid # In the realm of fragrance production, our project, named ‘Lights Control iT (intermixed Terpenoid)’, introduces an innovative approach to the controllable synthesis of two terpenoids as key fragrance components: santalol and sclareol. Traditional chemical synthesis methods generate substantial industrial waste, posing environmental challenges. To address these issues, we have designed a yeast-based cell factory capable of environmentally-friendly, controllable fragrance production.
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October 21, 2023
BNU-China # Silinker Universe: A biotoolbox for efficient modification of multiple biomolecules on mesoporous silica surfaces # Nanotechnology is experiencing rapid growth in both research and industrial communities. This provides new insights into tissue engineering, advanced pharmaceutics, and therapeutic application. Nanomaterials and nanostructures have unique physical and chemical properties, with advantages such as customizability and specificity. These advantages have driven the explosive development of nanomedicine over the last two decades.
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October 21, 2023
BOKU-Vienna # HormOWN # “Towards an Open-Source Biomanufacturing Protocol of Sex Hormones: Addressing Shortages of Testosterone using Synthetic Biology via De Novo Fermentation of Simple Carbon Sources in the yeast Pichia Pastoris”
“オープンソースの性ホルモン生産プロトコルに向けて：Pichia Pastoris酵母における単純炭素源からのデノボ発酵による、合成生物学を用いたテストステロン不足問題の解決”
reference:
iGEM BOKU-Vienna Team Information iGEM BOKU-Vienna Wiki
October 21, 2023
CAU-China # My Si-lium # In 2023, CAU China embarked on a purely biological manufacturing journey, drawing inspiration from mycilum and diatoms, and introduced a groundbreaking biotic material to the world, which we named ‘My Si-lium’. Our project comprises three phases. First, quorum sensing expressed the SulA gene, elongating bacterial monomers via filamentation. Next, Spytag was positioned on flagellar L-rings using FlgH, while SpyCatcher was displayed via Wza. Spytag was captured by SpyCatcher, cross-linking bacterial cells into a regular 3D network structure.
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October 21, 2023
Cornell # ENERGEM: Engineering Enzyme Reactions to Generate Methylxanthines # Methylxanthines are an important class of compounds used for various medical applications, including eye diseases, cardiovascular diseases, and respiratory illnesses. Cornell iGEM will be focusing on 7-methylxanthines in particular with ENERGEM to treat moderate to severe forms of myopia in patients where surgeries, such as LASIK or automated lamellar keratoplasty (ALK), cannot be performed. Traditional chemical synthesis methods produce low yields of these compounds, which contribute to expensive market prices for the medications that require them.
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October 21, 2023
GeorgiaState-SWJTU # Bio-Barbie: Co-culturing C. reinhardtii and E. coli for PHB Production # As evidenced by climate change and plastic pollution, it has become increasingly necessary to develop an alternative to fossil-fuel based production, such as biologically-based production. Our project’s aim is to create a polyhydroxybutyrate (PHB) production platform based on a co-culture between C. reinhardtii and E. coli. Such a co-culture has been shown to nearly double the growth of C.
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October 21, 2023
GXU-China # Microbial production of curcumin as a mildew-proof bio-pigment material. # Curcumin is a natural compound extracted from zingiberaceae, which has attracted worldwide attention because of its antioxidant, anticancer and mildew-proof functions. At present, the method of extracting curcumin from plants is squeezing and dissolving, which consumes a lot of energy and the output is far from meeting the market demand. At the same time, traditional mineral pigments are harmful to human body, while biological pigments are healthier.
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October 21, 2023
Hopkins # Synthesis of Caddisfly Fibroin Proteins: Using Prokaryotic Cells for Manufacturing Scale-Up # Silk production is a highly labor-intensive process, with additional human ethics complications in predominately lower-income regions. We propose an alternative process of silk production through the synthesis of heavy and light chain silk fibroin proteins using expression in prokaryotic cells. This process could then be scaled for mass production with bioreactors. Caddisfly silk fibroin was studied in this project due to its unique underwater adhesive properties and thermal resistance.
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October 21, 2023
HUBU-HUBEI-CHINA # Seed Player: Metabolic Engineering of B. licheniformis For Enhanced Hydroxytyrosol Production # Hydroxytyrosol (HT) is a polyphenol found in olives, known for its antioxidant and anti-inflammatory properties. However, its large-scale application is limited due to the high production costs associated with traditional plant extraction and chemical synthesis methods. Microbial production offers a promising alternative but faces challenges such as low strain tolerance, complex synthesis pathways, and oxidative degradation.
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