ucp1-delivery

NUDT-CHINA

October 21, 2023
arror, ucp1-delivery, photorhabdus-virulence-cassette-(pvc)-nanoparticles
therapeutics

NUDT-CHINA # ARROR: a PVC-Based delivery of UCP1 into adipose tissue for efficient body weight control # In the past 50 years, significant progress has been made in managing diseases closely linked to excess body weight. However, treating obesity itself has been challenging, with medications often providing inadequate efficacy and potential safety concerns. Here, we demonstrate a novel synthetic biology-inspired therapeutic nanomachine to reduce excess body fat by effectively delivering Uncoupling protein 1 (UCP1) into white adipose cells. ...