Guangxi-U-China

October 21, 2023

Guangxi-U-China # Engineered Bacteria with Nano-Immunomodulator for Precision Therapy of Triple Negative Breast Cancer # Triple negative breast cancer is the most aggressive subtype with poor prognosis and high risk of recurrence. The treatment is challenging because of limited chemotherapy responses, lack of actionable targets and acquired resistance to immune checkpoint inhibitors-based therapies. In particular, the acidic and hypoxic microenvironment caused by the high glycolytic activity of tumor cells promotes the non-inflammatory polarization of tumor-associated macrophages. ...