tfr1-high-expression

PekingHSC

October 21, 2023
neuraminidase-boost-influenza-virus, tfr1-high-expression, tumor-targeting
therapeutics

PekingHSC # Neuraminidase-boost Influenza Virus to Target Tumors with TFR1 high expression # Cancer is a great threat to human health, and the development of new antitumor therapies is imminent. Studies have shown that TfR1 (transferrin receptor 1) is highly expressed in many types of tumor cells, and it is also found that influenza virus uses the internalization pathway of TfR1 to achieve virus endocytosis, and this process is produced by the interaction between NA protein (neuraminidase) on the surface of the virus and TfR1. ...