silk-production-scale-up

Hopkins

October 21, 2023
caddisfly-fibroin-proteins, prokaryotic-cells, silk-production-scale-up
biomanufacturing

Hopkins # Synthesis of Caddisfly Fibroin Proteins: Using Prokaryotic Cells for Manufacturing Scale-Up # Silk production is a highly labor-intensive process, with additional human ethics complications in predominately lower-income regions. We propose an alternative process of silk production through the synthesis of heavy and light chain silk fibroin proteins using expression in prokaryotic cells. This process could then be scaled for mass production with bioreactors. Caddisfly silk fibroin was studied in this project due to its unique underwater adhesive properties and thermal resistance. ...