USP-EEL-Brazil

October 21, 2023

USP-EEL-Brazil # CBDynamics # Cannabidiol (CBD) is a valuable medical compound known for its numerous therapeutic benefits, particularly in treating epilepsy patients. However, in Brazil, its acquisition is shrouded in bureaucratic and legal complexities, primarily stemming from its association with Cannabis sativa. Therefore, this study aims to produce cannabidiolic acid (CBDA), the direct precursor to CBD, using biosynthesis and recombinant gene technology with Saccharomyces cerevisiae yeast. This production involves two essential pathways: the geranyl diphosphate (GPP) one, already present in the yeast metabolism, and the olivetolic acid rote. ...