IIT-Madras

October 21, 2023

IIT-Madras # Synthopedia # The absence of many genetic and regulatory libraries in unconventional chassis makes building genetic circuits and assemblies extremely difficult. There is an emerging need to explore new chassis which may be naturally adapted to unique traits or metabolic pathways. Lactococcus lactis (L. lactis) is one such ‘Generally Regarded As Safe’ (GRAS) organism that produces a range of products. Since the ability to fine-tune gene expression forms a cornerstone for the design and operation of genetic circuits, our project intends to construct and test a library of synthetic 5’ Untranslated Regions (UTR) containing Ribosome binding sites (RBS) in L. ...