prolyl-endopeptidases

UM-Macau

October 21, 2023
celiac-disease, prolyl-endopeptidases, microbe-based-therapeutics
therapeutics

UM-Macau # GEIG: Gluten Enzymatic Intestinal Guardians # Celiac Disease (CD) is the worldwide autoimmune gluten intolerance disease. Current treatments include lifelong gluten-free diets and oral enzyme therapy, but these therapies bring inconvenience to patients’ lives and the latter is still immature. UM-Macau aims to establish a rapid and targeted delivery and adhesion system that releases prolyl endopeptidases through probiotics under the control of NO sensors, as an alleviator of inflammatory-like environmental factors in CD intestine. ...