McGill

October 21, 2023

McGill # Proteus - A programmable and modular oncogene targeting and pyroptosis inducing system # Prevalence of cancer has been on the rise in the last twenty years, with cancers like pancreatic cancer still not improving in terms of treatment options. We engineered a novel, personalized therapeutic technique. A personalized treatment modality restricts negative off-target effects, ideally killing cancerous cells before surgical resection becomes the only viable treatment. We utilize the newly discovered CRISPR system, Craspase, to engineer forced pyroptotic cell death among cancerous cells. ...