Washington

October 21, 2023

Washington # Computational Design of NpRdhA for bioremediation of PCBs # Polychlorinated biphenyls (PCBs) are widespread persistent pollutants that pose a health risk to humans and wildlife. While bioremediation of PCBs has been demonstrated in bacteria expressing the biphenyl degradation pathway (bph gene cluster), efficiency varies depending on the number and position of the PCB chlorines. A critical step for bioremediation of PCBs is therefore the removal of PCB chlorine atoms catalyzed by dehalogenase enzymes. ...