mirna-detection

BPI-China

October 21, 2023
mirna-detection, myocardial-infarction, crispr-technology
diagnostics

BPI-China # Detection of mutiple miRNAs based on isothermal amplification on colloidal gold and CRISPR technology # Myocardial infarction is a common disease worldwide. There are approximately 330 million current heart attack victims in China. miRNA was considered as one of the most potential new biomarkers of myocardial infarction.Therefore, the development of miRNA detection methods is of great significance. The design idea of this project was to modify the hairpin structure on the surface of colloidal gold particles, and then the target miRNA could open the hairpin structure to initiate isothermal amplification reaction. ...