inflammatory-bowel-diseases

NWU-CHINA-A

October 21, 2023
inflammatory-bowel-diseases, engineered-probiotics, escherichia-coli-nissle-1917
therapeutics

NWU-CHINA-A # Super Probiotics: Intestinal Knight Engineered Bacteria Beat IBD # Our project focuses on the treatment of Inflammatory Bowel Diseases ( IBD ) by constructing engineered probiotics . The concentration of reactive oxygen species ( ROS ) is an important factor in the occurrence and development of IBD . We plan to express Catalase ( CAT ) , superoxide dismutase ( SOD ) and Elafin ( an endogenous human protein that inhibits neutrophil-derived serine proteases elastase and protease-3 ) in probiotics Escherichia coli Nissle 1917 . ...