UFlorida

October 21, 2023

UFlorida # Multifaceted Model to Study Sepsis Progression # Sepsis is defined as the body’s extreme response to infection and causes immune dysregulation, which leads to inflammation and a cascade of changes that damages organ systems. The pathophysiology of sepsis is inextricably linked to bone marrow, as the hematopoietic niche controls the proliferation of myeloid and lymphoid progenitor cells in peripheral blood and boosts local immune response. Tracking the progression of sepsis and predicting the clinical outcome is difficult, as no model exists that accurately mimics human physiology or immune trends. ...