MIT

October 21, 2023

MIT # CAR-P Diem: Seize the day! # Cancer cachexia is a severe muscle and fat wasting disease which directly causes 30% of cancer-related deaths, yet it is strikingly understudied. No treatments exist beyond exercise and diet regimens in the United States. The MIT iGEM team proposes CAR-P Diem: a therapy using macrophages equipped with a chimeric antigen receptor that specifically recognizes and phagocytoses interleukin 6 (IL-6) via an extracellular anti-IL6 antibody. ...