egf-ligand

Princeton

October 21, 2023
interkingdom-communication-pathway, egf-ligand, car-t-therapy
foundational advance

Princeton # Stick and Secrete: Building an Interkingdom Communication Pathway Between Bacteria and Mammalian Cells # We aim to develop a novel “stick-and-secrete” bacterial-mammalian cell communication system where engineered bacteria selectively adhere to mammalian cells, then secrete a ligand to elicit a particular response in the mammalian cell. This project is designed to be a modular toolbox that can provide a diverse array of highly localized responses in mammalian cells for scientific research. ...