e.codrop

Harvard

October 21, 2023
e.codrop, atps-droplet-suspended-cell-free-extract-systems, molecular-detection-systems
foundational advance

Harvard # E.CoDROP: Rapid Production of ATPS Droplet-Suspended Cell-Free Extract Systems # Research and diagnostic tools for high-throughput molecular detection can typically target only a single analyte or class of analytes at a time. One approach to addressing this shortcoming is suspending cell-free expression (CFE) detection systems in aqueous two-phase system (ATPS) droplets, then spatially assembling different protocell droplets into an assay capable of detecting diverse analytes. However, this approach necessitates costly preparation of cell-free lysates. ...