de-novo-biosynthesis

Yale

October 21, 2023
de-novo-biosynthesis, daidzein-production, (s)-equol-menopause-treatment
biomanufacturing

Yale # De Novo Biosynthesis of Daidzein for the Production of (S)-Equol # Menopause affects the majority of women approaching the age of 50 and introduces a host of adverse symptoms, such as cardiovascular diseases, and vasomotor and musculoskeletal issues. (S)-equol, an isoflavandiol estrogen produced in the human gut microbiome, has been found to help alleviate post-menopausal symptoms with minimal health risks. However, its effectiveness in the human gut is limited by its low production levels. ...