cyclic-peptide-production

Latvia-Riga

October 21, 2023
cyclic-peptide-production, burp-domain-proteins, bioactive-potential
foundational advance

Latvia-Riga # Full Circle: Advancing Cyclic Peptide production using BURP Domain proteins # BURP domains are a class of plant proteins that catalyze the cyclization of small peptide motifs, that have a potential to generate cyclic peptide therapeutics, antimicrobials and insecticides. Our goal is to produce functional recombinant BURP domain proteins in order to perform cyclisation of diverse (natural, engineered) peptide substrates. This would demonstrate a useful platform for realising the bioactive potential of cyclic peptides. ...