colorectal-cancer-therapy

GEC-Guangzhou

October 21, 2023
nissle-1917, colorectal-cancer-therapy, cytosine-deaminase
high-school

GEC-Guangzhou # Targeted therapy for colorectal cancer # We used Nissle 1917 as the chassis microbe because it is safe, reliable and easy to edit for the human body. We designed two modules of targeting and therapy. For the targeted part, we fusion expression of INP and HIPA genes, INP can anchor HIPA to the cell wall of engineered bacteria, and HIPA protein can recognize and bind to the receptor protein on the surface of cancer cells. ...