NMU-China

October 21, 2023

NMU-China # Gut-Sweeper: an engineered E. coli that integrates prevention, monitoring and treatment of constipation # Functional constipation is prevalent among the elderly, which gains an increasing concern as the population ages. In keeping with our view of “local people solve local problems”, we have designed our Gut-Sweeper, namely, an engineered E. coli that integrates prevention, monitoring, and treatment of constipation. We firstly empowered our engineered bacteria with monitoring ability by the butyrate sensory module, which can detect a distinct lowered butyrate concentration, a research-proven constipation marker. ...