butyl-butyrate-production

Nanjing-SDG

October 21, 2023
directed-evolution, clostridium-tyrobutyricum, butyl-butyrate-production
high-school

Nanjing-SDG # Directed Evolution of Clostridium Tyrobutyricum to Improve Butyl Butyrate Production # The increasing depletion of traditional energy and the greenhouse effect pose challenges to global sustainable development. Butyl butyrate’s low viscosity and low carbon emission make it a biofuel with a high potential of alleviating the above problems. We genetically engineered C. tyrobutyricum to enable efficient and large-scale synthesis of butyl butyrate. We optimize metabolic pathways through three strategies to further reinforce the synthesis of butyrate and butanol, including precursor accumulation, inhibition of byproducts, and increasing mass transfer efficiency as well as promoter engineering. ...