USAFA

October 21, 2023

USAFA # Lyme-AID: Genetically Engineered Detection of Borrelia burgdorferi, the causative agent of Lyme Disease # The USAFA iGEM 2023 team is working to improve rapid, on-the-spot, detection technology for Borrelia burgdorferi from an infected tick bite. This lyme sensing biosensor, bandaid-like patch, will be called Lyme-AID. A three-step approach will be used in this biosensor: Attract, Inhibit, and Detect (AID). Attract(1) B. burgdorferi to the biosensor patch and also limit diffusion of the pathogen into the new host through expression of Salp12, an Ioxodes scapularis salivary gland protein that acts as a chemoattractant for B. ...