artificial-biochemical-circuit

BUCT-China

October 21, 2023
polymerase-enabled-molecular-computing, dna-molecular-probes, artificial-biochemical-circuit
diagnostics

BUCT-China # POMELO:Polymerase- enabled Molecular Computing # Biological molecule diagnostics hold great promise in the field of healthcare. The BUCT-China team has developed DNA molecular probes capable of weighted summation calculations through polymerase-mediated strand displacement reactions. These probes, organized into an artificial biochemical circuit resembling a neural network structure, can execute weighted summation on multidimensional biomarker input signals, providing more intuitive low-dimensional diagnostic results for in vitro diagnostics and disease identification. ...