aroma-anchor-ambergris

LINKS-China

October 21, 2023
aroma-anchor-ambergris, santalwood-oil, yeast-cell-factory
high-school

LINKS-China # Aroma Anchor # AmbergrisĀandĀSandalwoodĀOilĀareĀbothĀwell-knownĀfragranceĀfixativesĀsinceĀcenturiesĀbefore. However, people hunted and killed sperm whales to obtain ambergris and the growing of sandalwood is highly time and cost consuming. LINKS-China 2023 aims to produce ambrein and santalol, the major components of the fixatives using yeast cell-factory. By engineering S.cerevisiae, we optimized the MVA pathways by over expressing tHMG1 and IDI1. Then, we constructed the pathway of santalene production by expressing ClSS and its mutant. ...