LINKS-China
October 21, 2023
LINKS-China # Aroma Anchor # AmbergrisĀandĀSandalwoodĀOilĀareĀbothĀwell-knownĀfragranceĀfixativesĀsinceĀcenturiesĀbefore. However, people hunted and killed sperm whales to obtain ambergris and the growing of sandalwood is highly time and cost consuming. LINKS-China 2023 aims to produce ambrein and santalol, the major components of the fixatives using yeast cell-factory. By engineering S.cerevisiae, we optimized the MVA pathways by over expressing tHMG1 and IDI1. Then, we constructed the pathway of santalene production by expressing ClSS and its mutant. ...