acnedote

RDFZ-CHINA

October 21, 2023
acnedote, egf-growth-factor, lcfa-absorption
high-school

RDFZ-CHINA # Acnedote: Innovative acne treatment via EGF growth factor and LCFA absorption. # In recent years, acne has emerged as a leading cause of appearance-related anxiety among adolescents, affecting approximately 94-95% of pubertal individuals worldwide. While there are existing topical treatments, their effectiveness is often unsatisfactory. Therefore, we aim to utilize synthetic biology techniques to enhance E. coli Nissle 1917 for acne treatment. For the inflammatory stage of acne, we have engineered the expression of FadL/FadD metabolic pathway proteins to absorb and break down long-chain fatty acids(LCFAs) on the face, reducing inflammation. ...