WIST #

Disrupting Quorum Sensing and AHL Signaling to Combat Bacterial Soft Rot Disease in Orchids #

Orchids, renowned for their aesthetic appeal, ecological significance, and economic value, face a severe threat from bacterial soft rot disease caused by Dickeya fangzhongdai. This study focuses on combating the pathogen through the disruption of quorum sensing and AHL signaling. Dickeya fangzhongdai employs plant cell wall degrading enzymes (PCWDEs) and quorum sensing to initiate tissue degradation and disease development. By applying quorum quenching organisms capable of degrading AHL signals, the communication among bacteria can be hindered, effectively disrupting the production of PCWDEs. Additionally, the utilization of the aiiA gene encoding AHL lactonase allows for the degradation of AHL signaling molecules, further halting PCWDE production. This research project aims to protect orchid viability and agricultural productivity by offering a promising approach to combat Dickeya fangzhongdai. The findings have significant implications for orchid cultivation and provide insights into effective disease management strategies in agricultural settings.

花の中でも美しさ、生態学的意義、経済的価値で高く評価されるランは、Dickeya fangzhongdaiによる細菌性軟絹病の深刻な

reference:

• iGEM WIST Team Information
• iGEM WIST Wiki