Guangzhou-MedX

Guangzhou-MedX #

SAFe: Shikimic acid feed for healthy stockbreeding and sustainability #

Antibody-free animal breeding protects human health, reduces the problem of resistance, and improves food safety. Shikimic acid (SA) is an important biochemical metabolite in plants and microorganisms that is known for antimicrobial and anti-inflammatory activities. In our project, we engineered the native shikimate pathway of E. coli to accumulate SA more efficiently. We plan to use it as a feed additive for preventive use in livestock breeding during seasons of high disease incidence. It will help improve the immunity of livestock and poultry, reduce the use of antibiotics, and potentially huge economic losses, and achieve the goal of sustainability.

抗体フリーの動物飼育は人間の健康を保護し、耐性の問題を減少させ、食品の安全性を改善します。シキミ酸(SA)は、抗微生物活性と抗炎症活性で知られる植物と微生物の重要な生化学的代謝産物です。私たちのプロジェクトでは、大腸菌のネイティブシキミ酸経路を改変して、効率的にSAを蓄積させます。我々は、疾患発生率が高い季節に家畜の飼育で予防的に使用する飼料添加剤として使用する予定です。それは家畜と鳥類の免疫力を改善し、抗生物質の使用を減らし、潜在的には巨大な経済的損失を軽減し、持続可能性の目標を達成するのに役立ちます。

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Village: high-school